Aminopeptidase N is a receptor for hedgehog merbecoviruses
Min Jin, Victoria A. Jefferson, Zhe Zhao…·Michael C. Letko
This study identifies Aminopeptidase N as the receptor for hedgehog merbecoviruses and shows restricted cross-species receptor use.
Author
University of North Carolina at Chapel HillORCID 0000-0002-6099-8429Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Min Jin, Victoria A. Jefferson, Zhe Zhao…·Michael C. Letko
This study identifies Aminopeptidase N as the receptor for hedgehog merbecoviruses and shows restricted cross-species receptor use.
Jordan Anderson-Daniels, Meghan V. Diefenbacher, Boyd L. Yount…·Timothy Patrick Sheahan
This study shows that SARS-CoV-2 with impaired nsp14-exonuclease activity has reduced replication, fitness, and pathogenesis, but remains viable in some conditions.
Mera F. Liccione, Trevor Scobey, Heather M. Froggatt…·Daniel Wrapp
This study isolates and characterizes neutralizing antibodies against HCoV-229E, showing one antibody induces conformational changes in the viral spike protein.
Nicholas J. Catanzaro, Ziyan Wu, Chengcheng Fan…·Michael C. Letko
The paper identifies ACE2 as a receptor for HKU5 coronaviruses from Pipistrellus abramus bats and investigates receptor tropism across merbecovirus clades.
Mia Madel Alfajaro, Emma L. Keeler, Ning Li…·Craig B. Wilen
This study identifies bat and mink ACE2 as receptors for HKU5 merbecovirus, revealing distinct receptor interactions and highlighting mustelids as potential intermediate hosts.