Wouter Hendrickx

This study shows SLFN11 enhances cisplatin sensitivity in pediatric cancers by modulating stress-response and survival pathways through epigenetic regulation and functional assays.

The paper investigates how inflammation reprograms goblet cells into tumor-initiating cells in colon cancer using single-cell RNAseq and mutation spectrum analysis.

This study identifies immune subtypes of colorectal cancer using methylation patterns, linking them to distinct clinical outcomes and immune programs.

This study investigates how MUC2 expression affects immune infiltration in colorectal cancer using in vitro models and CRISPR knockout, finding that MUC2 loss increases immune infiltration only in HT-29 cells.

The paper provides R scripts for analyzing and visualizing blood transcriptional module repertoires, demonstrating their application in septic patients' transcriptome data.

The paper investigates FAM129A expression in neutrophils exposed to sepsis serum using transcriptome data and confirms surface expression through bench validation.

The paper investigates NUDT16 transcript abundance in sepsis using omics data and public datasets, finding elevated levels in septic patients compared to controls.