Yaan‐Kit Ng

This study quantifies global PPI changes in skeletal muscle insulin resistance using PCP-MS and qXL-MS, revealing dysregulated interactions with chaperones and PDIA6.

The paper quantifies UFMylation sites in mouse tissues and ALS patient biopsies, finding increased myosin UFMylation in ALS.

This study characterizes the skeletal muscle arginine methylome in health and disease, revealing significant remodeling in ALS and identifying potential therapeutic targets.

The paper identifies C18ORF25 interactors and characterizes its role in skeletal muscle physiology using mass spectrometry and single fiber proteomics.

The paper identifies UFMylation as a negative regulator of skeletal muscle function through proteome-wide systems genetics in mice and validates it in a disease model.