Maria F. Gonzalez-Aponte

This study shows that viral replication byproducts called cbVGs drive changes in circadian gene expression during infection through distinct immune pathways, with ARNTL2 playing a key role in amplifying antiviral responses.

This study shows that daily glucocorticoids influence glioblastoma growth and circadian synchronization with the host, with effects dependent on timing and clock genes.

This study shows that TMZ efficacy in glioblastoma varies with time-of-day due to circadian rhythms in MGMT expression and promoter methylation, with optimal treatment at the peak of Bmal1 expression.