Author

Anna R. Damato

Washington University in St. LouisORCID 0000-0003-3283-3958Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Erik D. HerzogiD· 2 shared Maria F. Gonzalez-AponteiD· 2 shared Tatiana SimoniD· 2 shared Diego A. GolombekiD· 1 shared Fabrizio DarbyiD· 1 shared Gary J. PattiiD· 1 shared Jingqin Rosy LuoiD· 1 shared Joshua B. RubiniD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersNeuroscience

Erik D. HerzogORCID

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2 papers

Recent·Most cited

NeuroscienceCancer CellPeer-reviewedDec 12, 2024

Daily glucocorticoids promote glioblastoma growth and circadian synchrony to the host

Maria F. Gonzalez-Aponte, Anna R. Damato, Tatiana Simon…·Erik D. Herzog

This study shows that daily glucocorticoids influence glioblastoma growth and circadian synchronization with the host, with effects dependent on timing and clock genes.

39 citationstop 1%

mousehuman

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Cancer BiologybioRxivPreprintSep 13, 2023

Circadian regulation of MGMT expression and promoter methylation underlies daily rhythms in TMZ sensitivity in glioblastoma

Maria F. Gonzalez-Aponte, Anna R. Damato, Laura Lucía Trebucq…·Erik D. Herzog

This study shows that TMZ efficacy in glioblastoma varies with time-of-day due to circadian rhythms in MGMT expression and promoter methylation, with optimal treatment at the peak of Bmal1 expression.

DOI 10.1101/2023.09.13.557630

mousehuman

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