A STAT5B-driven mouse model of hepatosplenic γδ T-cell lymphoma reveals therapeutic efficacy of JAK inhibition
Myint Myat Khine Aung, Susann Schönefeldt, Sophie Pfalz-Kraupp…·Heidi Anne Neubauer
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University of Veterinary Medicine ViennaORCID 0000-0002-8416-1236Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
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Myint Myat Khine Aung, Susann Schönefeldt, Sophie Pfalz-Kraupp…·Heidi Anne Neubauer
Michelle C. Buri, Mohamed R. Shoeb, Aleksandr Bykov…·Eva Maria Putz
This study shows NK cells influence all phases of cancer immunoediting in B-ALL, promoting resistant clones through selective pressure and identifying LY6E as a marker of poor prognosis.
Klara Klein, Sebastian Kollmann, Angela Hiesinger…·Dagmar Gotthardt
This paper creates a mouse model with a STAT5BN642H mutation to study NK-cell leukemia and finds it leads to both indolent and aggressive forms of the disease.