Author

Scot A. Marsters

GenentechORCID 0000-0002-8517-0994Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Avi AshkenaziiD· 2 shared David A. LawrenceiD· 2 shared Cary D. AustiniD· 1 shared Catarina J. GaspariD· 1 shared David C. DeWitt· 1 shared David KaniD· 1 shared Ehud Segal· 1 shared Ioanna OikonomidiiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersCancer Biology

Avi AshkenaziORCID

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2 papers

Recent·Most cited

Cancer BiologyPLoS BiologyPeer-reviewedApr 10, 2025

A nonenzymatic dependency on inositol-requiring enzyme 1 controls cancer cell cycle progression and tumor growth

Iratxe Zuazo-Gaztelu, David A. Lawrence, Ioanna Oikonomidi…·Avi Ashkenazi

This study identifies a nonenzymatic role of IRE1 in cancer cell cycle progression and tumor growth, independent of its kinase-RNase activity.

16 citationstop 5%

humanexperimental assay

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Cell BiologybioRxivPreprintOct 24, 2024

TRAIL induces caspase-dependent cleavage of specific components of the clathrin-mediated endocytosis machinery

David A. Lawrence, Scot A. Marsters, Cary D. Austin, Avi Ashkenazi

This study shows TRAIL induces caspase-dependent cleavage of AP2 and CHC, with AP2 cleavage requiring caspase-8 and CHC cleavage requiring both caspase-8 and caspase-3.

DOI 10.1101/2024.10.24.619217

proteomicsexperimental assay

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