Jiří Zahradník

This study uses in vitro evolution to show that stringent selection pressures rapidly converge on Omicron-like mutations in SARS-CoV-2 spike protein, mirroring real-world viral evolution patterns.

This paper introduces a system for functionalizing extracellular vesicles with nanobody adapters, enabling flexible and efficient attachment of target proteins without genetic engineering of cells.

This study shows IRF1 regulates antiviral immunity through both cytokine signaling and direct promoter binding, affecting gene expression in a context-dependent manner.

This study investigates the virological properties of the SARS-CoV-2 JN.1 variant, focusing on its mutations and potential immune evasion capabilities.