Author

Ana Laura Chiodetti

Immunocore (United Kingdom)ORCID 0000-0002-7243-2131Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:flow cytometry· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Alexandra E. CuaycaliD· 1 shared Andrew M. LaddiD· 1 shared Andrew MuiriD· 1 shared Arianne C. RichardiD· 1 shared Audrey GérardiD· 1 shared Denise Minerva DrotariD· 1 shared Dylan SmurlickiD· 1 shared Edward A. PhelpsiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBioengineering

Alexandra E. CuaycalORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintMar 20, 2026

Transient immune landscape remodelling shapes CD8 T-cell priming during infection

Ana Laura Chiodetti, Han Cai, Andrew Muir…·Audrey Gérard

The paper shows that transient immune architecture changes during infection protect low-affinity CD8 T-cell priming from Treg inhibition, ensuring broad T-cell responses.

DOI 10.64898/2026.03.18.712682

mouseflow cytometry

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BioengineeringbioRxivPreprintOct 21, 2025

Inhibition of cell-mediated immunity in type 1 diabetes by beta cell-targeted PD-1 agonists in pancreas tissue slices

Matthew W. Becker, Matthew E. Brown, Katherine Wiseman…·Edward A. Phelps

This study shows that ImmTAAI, a beta cell-targeted PD-1 agonist, inhibits T cell activity in human type 1 diabetes by increasing T cell motility and reducing cytokine secretion.

DOI 10.1101/2025.10.21.683528

humanproteomics

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