BiochemistryNature Chemical BiologyPeer-reviewed
Capturing Snapshots of Nucleosomal H2A K13/K15 Ubiquitination Mediated by the Monomeric E3 Ligase RNF168
Huasong Ai, Zebin Tong, Zhiheng Deng…·Man Pan
This study determines the cryo-EM structures of RNF168/UbcH5c-Ub/nucleosome complexes to elucidate the mechanism of H2A K13/K15 site-specific ubiquitination.
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