William M. Durham

The paper determines the structure of the Tad pilus alignment complex and shows it forms a periplasmic conduit for pilus extension.

This study shows that Pseudomonas aeruginosa uses spatial sensing, not temporal sensing, to detect chemical gradients during surface-based chemotaxis.

This study shows that C. difficile can evolve vancomycin resistance through two pathways, but resistance comes with fitness costs and sporulation defects that may limit its clinical impact.