Zachary J. Reitman

This study develops a mouse model of Ppm1d mutations in gliomas, showing they deregulate the p53 pathway, promote gliomagenesis, and increase radiosensitivity and PARP inhibitor vulnerability.

This study investigates FLASH radiation effects on rat brain tissue and tumors using a novel high-energy electron beam, finding differential immune responses and microglial changes.

This study shows that disrupting ATM enhances radiation therapy efficacy in p53-mutant DMGs but not p53-wildtype DMGs using mouse models.