Nerissa T. Williams

This study develops a mouse model of Ppm1d mutations in gliomas, showing they deregulate the p53 pathway, promote gliomagenesis, and increase radiosensitivity and PARP inhibitor vulnerability.

The paper compares radiation response in autochthonous and transplant sarcomas in mice with and without adaptive immunity, finding higher cure rates in transplant tumors with immune function.

This study evaluates mini-GRID radiotherapy combined with anti-PD-1 in a murine tumor model, finding no improvement in tumor growth delay or survival compared to conventional radiotherapy.

This study shows that disrupting ATM enhances radiation therapy efficacy in p53-mutant DMGs but not p53-wildtype DMGs using mouse models.

This study shows that combining radiotherapy with CpG, a TLR9 agonist, enhances tumor response in a mouse sarcoma model by boosting CD8 T cell activity.

This study shows that p53 TAD1 regulates the DNA damage response in endothelial cells to prevent radiation-induced cardiac injury.