Author

Zainul S. Hasanali

University of PennsylvaniaORCID 0000-0002-9150-089XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Approach:biophysical modeling· 1 Research Focus:cancer & tumor microenvironment· 1 Approach:deep learning· 1

Frequent Co-Authors

Dan T. VogliD· 3 shared David AllmaniD· 3 shared Adam D. CoheniD· 2 shared Adam Justin WaxmaniD· 2 shared Alfred L. GarfalliD· 2 shared Sandra P. Susanibar-AdaniyaiD· 2 shared Andrei Thomas‐TikhonenkoiD· 1 shared Annette CastroiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersCancer Biology

Dan T. VoglORCID

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintMay 18, 2026

Mast Cells Enhance Myeloma Engraftment and Promote Bone Destruction in the NSG-hIL6 Patient Derived Xenograft Model

Zainul S. Hasanali, Alfred L. Garfall, Dan T. Vogl…·David Allman

This study shows mast cells enhance myeloma engraftment and promote bone destruction in the NSG-hIL6 xenograft model by secreting factors that improve myeloma cell survival.

DOI 10.64898/2026.05.14.725220

humanbulk RNA-seq

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Cancer BiologybioRxivPreprintJan 26, 2026

The ancestral haplotype of P2RX5 yields a B-cell surface marker and a multi-lineage immunotherapy target

Zhiwei Ang, Annette Castro, Luca Paruzzo…·Andrei Thomas‐Tikhonenko

The paper identifies P2RX5 as a new B-cell surface marker and multi-lineage immunotherapy target, showing its expression in B-cell malignancies and T-cell leukemia, and demonstrating the efficacy of P2RX5-directed therapies.

DOI 10.64898/2026.01.14.698748

humanbulk RNA-seq

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Cancer BiologyJCI InsightPeer-reviewedMay 7, 2024

Human IL-6 fosters long-term engraftment of patient derived disease-driving myeloma cells in immunodeficient mice

Zainul S. Hasanali, Alfred L. Garfall, Lisa M. Burzenski…·David Allman

The paper establishes NSG+hIL6 mice as a model for studying multiple myeloma by showing they support engraftment of patient-derived myeloma cells and develop disease features.

13 citations

humanbulk RNA-seq

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