Saurabh Singh Parihar

This paper identifies SARS-CoV-2 PLpro as a driver of epithelial stress and tissue damage across species by activating metabolic and inflammatory pathways in Drosophila and mammalian models.

This study shows that RasG12V-induced epithelial senescence in Drosophila triggers host metabolic syndrome through cytokine signaling, linking oncogene-induced senescence to metabolic disorders.

This study shows that Yki signaling suppresses PI3K/Akt/TOR in Drosophila squamous epithelia, preventing tumor formation, and that its loss leads to cancer-like changes in multiple tubular organs.

The paper shows that degenerating larval epidermal cells generate pull forces that drive thorax closure in Drosophila by contracting and shrinking, facilitating HE migration and zipping.