Cell BiologyCell ReportsPeer-reviewed
A Fkh1/2 binding site array in the WHI5 promoter drives sub-scaling transcription
Jacob Kim, Shicong Xie, Lucas Fuentes Valenzuela…·Jan Marcel Skotheim
3 citationstop 3%
Author
Jacob Kim
Stanford UniversityORCID 0000-0002-9306-4446Unclaimed ORCID profile · follow to get notified of new preprints
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Biology Disciplines
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- Cell BiologybioRxiv
Genome dilution by cell growth drives starvation-like proteome remodeling in mammalian and yeast cells
Michael C. Lanz, Shuyuan Zhang, Matthew P. Swaffer…·Jan M. Skotheim
The paper shows that increasing cell size leads to proteome remodeling similar to starvation, driven by genome dilution in mammalian and yeast cells.
- Molecular BiologybioRxivPreprint
Whi5 is diluted and protein synthesis does not dramatically increase in pre-Start G1
Kurt M. Schmoller, Michael Charles Lanz, Jacob Kim…·Jan Marcel Skotheim
The paper challenges a model proposing that protein synthesis increases in pre-Start G1, finding that Whi5 concentration remains constant and Cln3 increase is not due to synthesis.
1 citation