Zixi Wang

SMORE performs joint dimensionality reduction and cell population discovery on single-cell methylome data, accurately recovering population structures in human datasets.

This study shows that liver cancer initiation depends on metabolic zonation but is not linked to premalignant clonal expansion.

This study shows that IGFBP2-expressing midlobular hepatocytes contribute to liver homeostasis and regeneration after injury or fasting.

This study shows that Arid1a loss enhances pancreatic β-cell regeneration by activating EGF signaling, protecting against diabetes.