Author
Nan Zhang
Howard Hughes Medical InstituteORCID 0000-0002-9675-5322Unclaimed ORCID profile · follow to get notified of new preprints
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Biology Disciplines
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2020-2026 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 24 mutual co-author links4 papers
Recent·Most cited
- BioinformaticsbioRxivPreprint
pertTF: context-aware AI modeling for genome-scale and cross-system perturbation prediction
Yangqi Su, Dingyu Liu, Vipin K. Menon…·Wei Li
The paper introduces pertTF, a transformer-based model for predicting genetic perturbation responses, showing improved performance in expression prediction and cell identity shifts across cellular contexts.
- NeuroscienceScientific ReportsPeer-reviewed
Regulation of Glypican 6-mediated Wnt activation maintains TDP-43 nuclear localization in neurons
Nan Zhang, Shanthini Sockanathan
This study identifies a signaling axis involving GDE2, GPC6, and the Wnt pathway that regulates NPC integrity and TDP-43 nuclear localization in neurons.
- NeurosciencePLoS ONEPeer-reviewed
Severe Hyposmia Distinguishes Neuropathologically Confirmed Dementia with Lewy Bodies from Alzheimer’s Disease Dementia
Thomas G. Beach, Charles H. Adler, Nan Zhang…·Richard C. Gerkin
This study finds that severe hyposmia (reduced sense of smell) is a distinguishing feature between dementia with Lewy bodies and Alzheimer’s disease dementia, based on neuropathological confirmation.
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