Dmitry Shvarev

This study uses cryo-EM to determine the structure of the CobST cobaltochelatase motor and reveals how ATP and CobT regulate its assembly and activation for cobalt chelation.

This study reports cryo-EM structures of human ABCA2, revealing its cholesterol transport mechanism and novel conformational changes.

The paper shows PII interacts with NAGK in two steps, with the B-loop initiating contact and the T-loop completing the complex formation.

The paper determines the structure of the ChlG2HliD2 complex using cryo-EM to elucidate chlorophyll synthesis and photoprotection mechanisms.

The paper uses cryo-EM to study P-glycoprotein in different environments, revealing distinct roles of transmembrane helices 4 and 10 in its functional plasticity.

This study systematically analyzes the conformational spectrum of the bacterial ABC transporter MsbA in twelve different membrane mimetics using cryo-EM, revealing environment-specific structural responses.

The paper investigates how OpcA regulates G6PDH in cyanobacteria through redox-dependent conformational changes, revealing a novel allosteric mechanism.

The paper solves the structure of the CORVET tethering complex using cryo-EM and explains its role in promoting endosome fusion through interactions with Rab5 and PI3P.