Author

Yang Xu

Arizona State UniversityORCID 0000-0002-9945-7507Unclaimed ORCID profile · follow to get notified of new preprints

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Yang Xu9 papers · Hong Kong University of Science and Technology

Biology Disciplines

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Bioengineering· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Approach:deep learning· 1 Assay:DNA methylation· 1 Assay:protein structure· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Abhay PrasadiD· 2 shared Hao YaniD· 2 shared Rong Zheng· 2 shared Adam Doherty· 1 shared Deeksha SatyabolaiD· 1 shared Erik PoppletoniD· 1 shared Hao LiuiD· 1 shared Jiapei Jiang· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersSynthetic Biology

Abhay PrasadORCID

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2 papers

Recent·Most cited

Synthetic BiologybioRxivPreprintSep 18, 2024

DNA-templated spatially controlled proteolysis targeting chimeras for CyclinD1-CDK4/6 complex protein degradation

Rong Zheng, Abhay Prasad, Deeksha Satyabola…·Hao Yan

This paper introduces DNA-templated PROTACs (DTACs) that enable precise spatial control over protein degradation, showing enhanced selectivity and potency in degrading the CyclinD1-CDK4/6 complex.

1 citation

protein structureexperimental assay

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BioengineeringbioRxivPreprintSep 18, 2023

IgG-inspired, multivalent protein-DNA nanostructures for high-affinity, tunable, and reversible binding to biomolecular targets

Rong Zheng, Yang Xu, Abhay Prasad…·Nicholas Stephanopoulos

This paper designs and tests a DNA-based synthetic antibody (nano-synbody) that binds SARS-CoV-2 spike proteins with high affinity and reversibility through multivalency.

3 citations

DNA methylationspatial transcriptomics

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