Dishary Sharmin

The paper shows that 5-GABA-A receptor positive allosteric modulation improves neuronal morphology and cognitive function in a mouse model of tauopathy without affecting p-Tau levels.

This paper develops non-sedating antischistosomal benzodiazepines by modifying meclonazepam's structure, identifying compounds effective in vivo with reduced sedation.

This study shows that extrasynaptic localization of 5GABAARs is critical for their ability to modulate dopamine system function, as shifting them to synaptic locations abolishes the effect of the 5-PAM GL-II-73.

This study investigates the effects of a 5-GABAAR positive allosteric modulator on ASD-like behaviors in a rat model, finding it reduces social and cognitive deficits without affecting dopamine system activity.

This study evaluates the effects of GABAA receptor modulators in a mouse model of chronic stress, showing antidepressant and pro-cognitive effects with neurotrophic benefits.