Author

Nicole C. Howard

Harvard UniversityORCID 0000-0003-0805-5914Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

Sarah M. FortuneiD· 2 shared Amanda N. D. AdamsiD· 1 shared Benjamin BrauneckeriD· 1 shared Caroline M. MitchelliD· 1 shared Cecilia A. WebberiD· 1 shared Cecilia Kim· 1 shared Dirk SchnappingeriD· 1 shared Douaa MugahidiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMicrobiology

Sarah M. FortuneORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

MicrobiologyNature MicrobiologyPeer-reviewedJan 10, 2025

Development of an Engineered Mycobacterium tuberculosis Strain for a Safe and Effective Tuberculosis Human Challenge Model

Xin Wang, Hong-Wei Su, Joshua B. Wallach…·Dirk Schnappinger

This paper develops an engineered Mycobacterium tuberculosis strain with kill switches for a safe TB human challenge model, showing rapid clearance and low escape rates.

27 citationstop 1%

genetic perturbation / CRISPR

𝕏 PostBluesky

MicrobiologyCell Host & MicrobePeer-reviewedOct 17, 2024

Vaginal lactobacilli produce anti-inflammatory beta-carboline compounds.

Virginia J. Glick, Cecilia A. Webber, Lauren E Simmons…·Smita Gopinath

This study identifies beta-carboline compounds produced by vaginal lactobacilli that reduce inflammation by suppressing immune signaling pathways and demonstrate therapeutic potential in a mouse model.

53 citationstop 1%

humanmouse

𝕏 PostBluesky