Min Gyu Lee

This study shows that heterozygous Kmt2d loss promotes medulloblastoma by enhancing tumor-promoting programs and that combining LSD1 inhibition with oxidative phosphorylation blockade reduces tumorigenicity.

The paper establishes a database of lung cancer mouse models to improve data comparison and translational relevance by aligning mouse mutations with human lung cancer mutations.

The paper introduces MACMIC, a method to identify feature pairs with maximal colocalization and minimal correlation, revealing CTCF's dual role in regulating cell identity genes through epigenetic mechanisms.