Dolly Mehta

This study shows that CD36-mediated lipid uptake causes endothelial stiffening, leading to barrier disruption and atherosclerosis in mouse models, with sex-dependent effects.

This study identifies a TRPC6 mutation that protects mice from acute lung injury by promoting endothelial regeneration and preventing vascular injury.

This study shows RGS2 limits IFNγ production in alveolar macrophages by inhibiting TLR4-Gαq signaling, reducing lung injury in mice and correlating with ARDS patient data.

This study shows that endothelial ERG regulates neutrophil transcriptome to create an anti-inflammatory vascular niche, preventing excessive inflammation.

The paper identifies matrimeres as nanoscale mediators of tissue integrity, showing they can restore vascular integrity after injury and are reconstituted from fibronectin, DNA, and acidic conditions.