Author

Nicolas Böhly

Universitätsmedizin GöttingenORCID 0000-0003-0988-7720Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Holger BastiansiD· 2 shared Alexander Haas· 1 shared Alexander van OudenaardeniD· 1 shared Anchel De Jaime-SogueroiD· 1 shared Andrei ChabesiD· 1 shared Anja BufeiD· 1 shared Anna Sophia JauchiD· 1 shared Annarita PatriziiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCancer Biology

Holger BastiansORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintDec 19, 2025

SMAD4 loss drives cancer chromosomal instability through transcription-replication conflict-induced replication stress

Atmika Paul, Gargee Joshi, Philipp Jungk…·Holger Bastians

This study shows SMAD4 loss causes cancer chromosomal instability by inducing replication stress through transcription-replication conflicts via BMP signaling.

DOI 10.64898/2025.12.17.694873

humanexperimental assay

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Cell BiologyNature CommunicationsPeer-reviewedAug 28, 2024

A signalling rheostat controls chromosome segregation fidelity during early lineage specification and neurogenesis by modulating DNA replication stress

Anchel De Jaime-Soguero, Janina Hattemer, Anja Bufe…·Sergio P. Acebrón

The paper identifies a signalling rheostat involving WNT, BMP, and FGF that modulates DNA replication stress and chromosome segregation fidelity during lineage specification and neurogenesis.

16 citations

humanmouse

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