Author

Lauren Toms

Medicines Discovery CatapultORCID 0000-0003-1058-0515Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:clustering· 1 Research Focus:development & morphogenesis· 1 Assay:electrophysiology· 1 Approach:experimental assay· 1 Assay:fluorescence / live-cell microscopy· 1 Organism:human· 1

Frequent Co-Authors

Alice S. WhitleyiD· 1 shared Andrew W. TraffordiD· 1 shared Callum J QuinniD· 1 shared Charlotte E. R. SmithiD· 1 shared Christian PinaliiD· 1 shared David A. EisneriD· 1 shared David Charles HutchingsiD· 1 shared Denis AlféreziD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperPhysiology

Alice S. WhitleyORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJan 14, 2026

Grading HER2 at the nanoscale in clinical tissue

Lauren Toms, Hervé Barjat, Isabel Peset…·Emily Offer

This study uses super-resolution microscopy to analyze HER2 nanoclustering in breast cancer tissues, revealing grade-dependent patterns and reclassifying samples based on nanoscale features.

DOI 10.64898/2026.01.14.695095

humanfluorescence / live-cell microscopy

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PhysiologyJournal of Molecular and Cellular CardiologyPeer-reviewedJan 4, 2026

Atrial t-tubules adopt a specialist developmental state while alterations to Ca2+ buffering maintain systolic Ca2+ during postnatal development

Charlotte E. R. Smith, Callum J Quinn, Jessica D. Clarke…·Katharine M. Dibb

This study examines atrial t-tubule development in sheep, showing that despite reduced density in newborns, Ca2+ handling is maintained through increased L-type Ca2+ current and sarcoplasmic reticulum content.

2 citationstop 5%

electrophysiologyexperimental assay

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