Nathalie M. Mazure

This study examines the effects of miR-210 locus deletion on cellular homeostasis in human and mouse cells, revealing deregulation of neighboring genes and unexpected lack of miR-210 target enrichment.

This study shows that Group 3 medulloblastoma cells rely on HIF-2 instead of HIF-1 for hypoxia adaptation, and inhibiting HIF-2 with metformin kills these cells more effectively than non-Group 3 cells.