BiochemistrybioRxiv
Conformational changes in the Niemann-Pick Type C1 protein NCR1 drive sterol translocation
Kelly M. Frain, Emil Dedic, Lynette Nel…·Bjørn Panyella Pedersen
This study identifies a glycocalyx in yeast vacuoles and presents cryo-EM structures of NCR1 showing conformational changes that drive sterol translocation across the glycocalyx.