Xiaoyue Hu

The paper uses cSTAR to analyze endothelial cell transcriptomic states under different flow conditions, identifies CDK2 as a key regulator of artery remodeling.

This study shows that atrial AMPK deletion shifts metabolism from fatty acid oxidation to pyruvate oxidation and disrupts metabolic pathways, contributing to atrial remodeling and arrhythmia.

This paper introduces RBET, a statistical framework to evaluate batch correction methods for single-cell transcriptomic data integration, showing it selects optimal tools for accurate downstream analysis.

This paper introduces non-parametric GWAS methods that reduce false negatives by addressing SNP coding strategy issues, showing improved performance in identifying significant genetic loci.