Author

Benjamin T. Porebski

Monash UniversityORCID 0000-0003-1398-0442Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Immunology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Approach:comparative / phylogenetic analysis· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Ashley M. BuckleiD· 2 shared Daniel ChristiD· 2 shared Alan Aderem· 1 shared Amanda Russell· 1 shared Anselm Enders· 1 shared Belinda Whittle· 1 shared Benjamin E. Clifton· 1 shared Carla Roots· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBiochemistry

Ashley M. BuckleORCID

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3 papers

Recent·Most cited

BiochemistryNature CommunicationsPeer-reviewedMar 7, 2025

Structure and dynamics of the autoantigen GAD65 in complex with the human autoimmune polyendocrine syndrome type 2-associated autoantibody b96.11

Susanne H. D. Ständer, Cyril F. Reboul, Sarah N. Le…·Ashley M. Buckle

This study characterizes the structure and dynamics of GAD65 and its interaction with autoantibody b96.11, revealing how intrinsic conformational flexibility drives autoantigenicity.

10 citations

humanstructural biology

𝕏 PostBluesky

Synthetic BiologybioRxivPreprintMar 3, 2021

Emergence of function from single RNA sequences by Darwinian evolution

Falk Wachowius, Benjamin T. Porebski, Christopher M. Johnson, Philipp Holliger

This study shows that functional RNAs can emerge from a single RNA sequence through mutation and selection, without requiring large random sequence pools.

2 citations

experimental assay

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ImmunologybioRxivPreprintMar 27, 2019

Phospho-tuning immunity through Denisovan, modern human, and mouse TNFAIP3 gene variants

Nathan W. Zammit, Owen M. Siggs, Paul Gray…·Shane T. Grey

The paper identifies TNFAIP3 variants in humans, Denisovans, and mice that modulate A20 phosphorylation, revealing a genetic mechanism for balancing immunity and microbial tolerance.

DOI 10.1101/589507

humanmouse

𝕏 PostBluesky