Petr Šulc

This paper introduces an experimental method to reconstruct free-energy landscapes of rotary DNA nanomachines using electric-field biasing and statistical reweighting, revealing energy barriers and design modifications' effects.

This paper introduces mRNA-OG, a programmable mRNA nanostructure that affects protein expression, delivery, and immune response through its architecture.

This paper develops a DNA-templated chiral metamaterial array for secure optical information storage using plasmonic chirality to encode binary data.

This paper develops a DNA origami cryptography protocol using high-speed 3D DNA-PAINT and unsupervised clustering to enhance encryption key size and information retrieval accuracy.

The paper quantifies viral mimicry in genomes across species and shows how repetitive elements maintain pathogen-like features under selection.

This paper introduces MATE magnetic cascades for nucleic acid detection, achieving improved sensitivity and faster assay times through mismatch-assisted toehold exchange.

This study shows that base distribution along an invading strand strongly affects DNA-RNA strand displacement kinetics, enabling design of sequences with reaction rates spanning two orders of magnitude.

This study uses single-molecule force spectroscopy to analyze the kinetics of toehold-mediated strand displacement, revealing sequence-dependent dynamics and load effects in DNA and RNA interactions.

This paper designs and tests a DNA-based synthetic antibody (nano-synbody) that binds SARS-CoV-2 spike proteins with high affinity and reversibility through multivalency.

This paper describes a method using DNA origami to guide the assembly of protein-DNA conjugates into programmable nanostructures with controlled stoichiometry and geometry.

The paper introduces a method to compare immune repertoires by identifying conserved macro-level features, enabling assessment of repertoire completeness from sampled sequences.

ExpertRNA is a modular framework that combines multiple rewards and prediction algorithms to improve RNA secondary structure prediction accuracy.

The paper analyzes CpG dinucleotide distribution in SARS-CoV-2, finding low average CpG content with fluctuations linked to immune evasion and replication strategies.

Complex+ integrates and curates protein interaction data to help researchers identify reliable interactors and guide future experiments.