Monika Vaitkevičiūtė

This study identifies two distinct mechanisms by which pancreatic cancer cells extravasate: protrusion-driven invasion and endothelial retraction, with implications for anti-metastatic strategies.

This study shows SHANK3 regulates endothelial cell motility and tissue mechanics, affecting vascular development in zebrafish and mice.

The paper shows filopodia can penetrate neighboring cells to form impact sites that initiate trans-endocytosis, with internalized tips often being double-membraned and associated with endoplasmic reticulum.

This study shows that leupaxin inhibits durotaxis and mechanosensitivity in metastatic breast cancer cells by disrupting paxillin-FAK signaling.

This study uses fast label-free live imaging and deep learning to analyze cancer cell arrest on endothelial monolayers, finding CD44-HA interactions and flow dynamics are key factors.

This study identifies TLNRD1 as a CCM complex component that regulates endothelial barrier integrity by modulating actin bundling.