Geraldine Nouailles

This study identifies CXCL5 as a factor that increases alveolar-epithelial barrier permeability in acute lung injury, independent of neutrophil recruitment.

This study investigates how phage-phage competition and biofilm formation affect the efficacy of a two-phage combination against Pseudomonas aeruginosa in vitro.

This study shows that pneumonia increases glucagon levels, which damages endothelial cells and promotes blood clotting, leading to cardiovascular issues.

This paper uses neural networks to match disease states between human and hamster COVID-19 scRNAseq data, finding similar cellular responses in specific cell types across species.

The paper compares single-cell RNA-seq data from hamster and human COVID-19 samples to identify a shared inflammatory axis and a neutrophil-endothelial program associated with severe disease.

This study shows that enzymatic degradation of hyaluronan and heparan sulfate in the lung worsens Streptococcus pneumoniae infection by increasing inflammation, bacterial burden, and barrier disruption in mice and human models.

The paper evaluates dexamethasone and anti-SARS-CoV-2 antibodies in hamster models, showing reduced viral burden with antibodies and anti-inflammatory effects with dexamethasone, with synergistic benefits when combined.