Ashley Utz

This study shows that sustained delivery of a SARS-CoV-2 subunit vaccine in an adjuvanted hydrogel depot improves antibody responses in nonhuman primates compared to bolus vaccination.

This paper develops a subcutaneous delivery platform for ultra-high-concentration protein therapeutics using a copolymer excipient, enabling reduced injection volumes and improved stability.

This paper improves mRNA vaccine efficacy by creating an inflammatory immune niche via injectable hydrogel depots that recruit immune cells and enhance humoral responses.

This paper describes engineering hematopoietic stem cells to produce CCR5 knockout cells and secrete HIV-1 inhibiting antibodies, aiming for a one-time cure for HIV-1.

This paper develops a multivalent liposomal hydrogel vaccine that generates broad and durable anti-coronavirus antibody responses in mice.

This study uses the PMD immunofocusing technique to create RBD immunogens that induce broadly neutralizing antibodies against the conserved cryptic face of SARS-CoV-2.

This paper designs universal Ebola virus vaccine candidates using hyperglycosylation to focus antibody responses on conserved epitopes, showing cross-neutralizing activity against multiple orthoebolavirus species.