Author

G. Johan A. Offerhaus

University Medical Center UtrechtORCID 0000-0003-2683-3986Unclaimed ORCID profile · follow to get notified of new preprints

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Assay:imaging· 1 Organism:mouse· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

A. R. Keijzer· 1 shared Alessandra MerendaiD· 1 shared C. Jamieson· 1 shared Despina Xanthakis· 1 shared Folkert H.M. MorsinkiD· 1 shared Frank C. P. HolstegeiD· 1 shared H. Ma· 1 shared Jelte van der VaartiD· 1 shared

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2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

A. R. Keijzer

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1 paper

Recent·Most cited

Cancer BiologyGastroenterologyPeer-reviewedOct 23, 2025

Intestinal LKB1 loss drives a pre-malignant program along the serrated cancer pathway

Susanna Plugge, H. Ma, Jelte van der Vaart…·Madelon M. Maurice

This study shows that LKB1 loss in intestinal cells leads to a pre-malignant state linked to serrated colorectal cancer, which is amplified by loss-of-heterozygosity.

6 citations

mousescRNA-seq

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