Khanh Huy Bui

CiliaBuilder2 enables flexible 3D visualization of ciliary structures from diverse data types in ChimeraX.

This study determines the structural and mechanical differences between two type V fimbriae in P. gingivalis, showing how structural tuning leads to distinct mechanical properties.

This study shows that SPEF1 stabilizes central microtubules in Tetrahymena cilia, with defects in its absence affecting ciliary structure and function.

The paper resolves the native structure of the Trichonympha centriole cartwheel using cryo-electron tomography, revealing a zigzag stacking pattern of SAS-6 tetramers and their role in structural stability and polarity.

CsMT provides a streamlined CryoSPARC workflow for cryo-EM reconstruction of microtubules, achieving high-resolution results with minimal manual intervention.

The paper investigates ribosome clusters in neuronal RNA granules, finding they contain stalled ribosomes and unique 3D structures that avoid quality-control mechanisms.

The paper presents a high-resolution structure of the ciliary tip central pair in Tetrahymena thermophila and identifies proteins that stabilize microtubules.

DomainFit identifies protein domains in low-resolution cryo-EM maps using AlphaFold2 models, revealing new proteins in cellular complexes.

This study examines how alpha-tubulin acetylation affects doublet microtubule structure in Tetrahymena cilia using cryo-EM, MD, and mass spectrometry, finding small-scale structural changes and a link to phosphorylation.