Michal Wieczorek

This study presents the cryo-EM structure of the C. elegans γ-TuRC, revealing how it templates 11-protofilament microtubules through a divergent 4-spoked assembly.

This study uses cryo-EM to resolve microtubule structures in different nucleotide states, revealing how GTP hydrolysis affects lattice stability and microtubule dynamics.

The paper reports the structure of the mammalian ciliary transition zone microtubule doublet using cryo-electron tomography, revealing unique proteins and their roles in microtubule stabilization and transport regulation.

The paper introduces MiCSPARC, a cryo-EM pipeline for microtubule structure determination, achieving high-resolution reconstructions of decorated and undecorated microtubules.

This study presents the cryo-EM structure of the R2C complex, revealing how CCDC103 interacts with RUVBL1-RUVBL2 to facilitate dynein motor assembly in PCD.

This paper reports cryo-EM structures of NEDD1 bound to the human γ-TuRC with and without CDK5RAP2, revealing how NEDD1 anchors the complex and orients its microtubule-binding domains.

This study determines the structure of the gamma-tubulin ring complex (gamma-TuRC) activated by CDK5RAP2 and shows how it promotes microtubule nucleation by closing the gamma-tubulin ring.