Noam Stern‐Ginossar

This study examines how HCMV and SARS-CoV-2 affect the human tRNA pool and finds HCMV alters tRNA expression and modifications, while SARS-CoV-2 does not, with implications for viral codon usage and host-virus interactions.

This study shows that reduced viral entry in monocytes leads to HCMV latency, while efficient entry enables productive infection, highlighting entry as a key determinant of latency.

This study shows that overexpression of HCMV IE1 or IE2 enhances productive infection, with IE2 driving early gene expression and IE1 disrupting PML nuclear bodies to promote lytic infection.

This study develops VECOS, a viral-encoded CRISPR screen to analyze host dependencies during cytomegalovirus infection, identifying novel factors and revealing the importance of virion assembly.

The paper introduces NOVA, a deep learning model for analyzing organelle structures in neurons, revealing novel ALS mechanisms through phenotypic changes in TDP-43 and P-bodies.

The paper examines dynamic changes in tRNA modifications and abundance during T-cell activation, finding reduced wybutosine and ms2t6A modifications that may increase ribosomal frameshifting and facilitate HIV infection.

The paper investigates functional compensation among Ythdf m6A readers in mouse gametogenesis and embryonic stem cells, revealing dosage-dependent redundancy and distinct roles.