Kosuke Tomimatsu

MEGA-FISH is a GPU-accelerated framework for spatial omics image analysis that improves processing speed and accuracy for large-scale tissue data.

The paper introduces PECAbs for high-specificity multiplexed imaging of cell states and combines them with seq-smFISH to classify cells and identify signal activation states in human tissue.

The paper introduces tsChIL, a method to analyze tissue-level epigenomic data from single-thin sections, enabling independent evaluation of cell population changes and gene activation in regenerating skeletal muscle.