NeuroscienceCurrent BiologyPeer-reviewed
Author
Demet Araç
University of ChicagoORCID 0000-0002-5444-5799Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2024-2026 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 26 mutual co-author linksFocal author (center)Selected co-authorORCID co-authorUnlinked name
Curved chords = mutual co-authorship5 papers
Recent·Most cited
- NeurosciencebioRxivPreprint
The Adhesion GPCR Flamingo-Like 1 (FMIL-1) Directs Synapse Formation in a Nociceptive Circuit
Tyler Kennedy, Damilola Oje, Kylie Howerter…·David M. Miller
The paper identifies FMIL-1 as a gene that directs synapse formation in a C. elegans nociceptive circuit by promoting connectivity between PVD neurons and PVC/AVA interneurons.
DOI 10.64898/2026.09.01.748526 - BiochemistryProceedings of the National Academy of SciencesPeer-reviewed
The far extracellular CUB domain of the adhesion GPCR ADGRG6/GPR126 is a key regulator of receptor signaling
Sumit J. Bandekar, Ethan E. Dintzner, Katherine Leon…·Demet Araç
This study investigates how the CUB domain of ADGRG6 regulates receptor signaling by modulating conformational dynamics of the extracellular region.
5 citations - BiochemistryNature CommunicationsPeer-reviewed
Structural analysis and conformational dynamics of a holo-adhesion GPCR reveal interplay between extracellular and transmembrane domains
Szymon P. Kordon, Kristína Cechová, Sumit J. Bandekar…·Demet Araç
This study uses cryo-EM and single-molecule FRET to show conformational coupling between the extracellular and transmembrane domains of an aGPCR, revealing how ECR dynamics influence receptor function.
28 citations - BiochemistrybioRxivPreprint
Structural basis for regulation of CELSR1 by a compact module in its extracellular region
Sumit J. Bandekar, Krassimira A. Garbett, Szymon P. Kordon…·Demet Araç
This study determines the structure of the CELSR1 extracellular region and shows how specific domains form a compact module to regulate cellular adhesion.
11 citations