Martin Craig Taylor

This study uses cardiac transcriptomics in mice to compare immune responses during acute and chronic Trypanosoma cruzi infection, identifying shared and divergent features.

The paper analyzes the transcriptome and proteome of quiescent T. cruzi epimastigotes to understand persistence mechanisms and improve drug development.

This study examines MCM protein expression and localization in Trypanosoma cruzi during metacyclogenesis and G1 arrest, revealing their role in cell cycle regulation and replication arrest.

This study shows that intermittent posaconazole treatment does not prevent cardiac and digestive tract pathologies in a chronic Chagas disease mouse model, even with high parasite burden reduction.

This study establishes a hamster model of Trypanosoma cruzi infection using bioluminescence imaging, revealing chronic tissue pathology and motor dysfunction not seen in mice.

The paper describes a panel of bioluminescent and fluorescent Trypanosoma cruzi strains to study Chagas disease, enabling real-time monitoring of infection dynamics and drug screening.