Cell BiologybioRxivPreprint
TECPR1 provides E3-ligase like activity to the ATG5-ATG12 complex to conjugate LC3/ATG8 to damaged lysosomes
Yingxue Wang, Matthew A. Jefferson, Matthew Whelband…·Thomas E. Wileman
This study shows TECPR1 can substitute for ATG16L1 to conjugate LC3 to damaged lysosomes by providing E3-ligase activity to the ATG5-ATG12 complex.
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