Author

Matthew A. Jefferson

University of East AngliaORCID 0000-0003-2133-9487Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:experimental assay· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Thomas E. WilemaniD· 3 shared Penny P. PowelliD· 2 shared Agatha TreveiliD· 1 shared Alastair J.M. WatsoniD· 1 shared Benjamin BoneiD· 1 shared Christopher J. MorrisiD· 1 shared Derek T WarreniD· 1 shared Devina P Divekar· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersCell Biology

Thomas E. WilemanORCID

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3 papers

Recent·Most cited

Cell BiologyAutophagyPeer-reviewedMar 28, 2025

ATG16L1 WD domain regulates lipid trafficking to maintain plasma membrane integrity to limit influenza virus infection

Benjamin Bone, Luke Griffith, Matthew A. Jefferson…·Penny P. Powell

2 citations

mouseproteomics

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Cell BiologyJID InnovationsPeer-reviewedApr 27, 2024

The WD Domain Of Atg16l1 Crucial For LC3-Associated Phagocytosis Is Not Required For Preserving Skin Homeostasis In Mice

Shannon Conway, Matthew A. Jefferson, Derek T Warren…·Christopher J. Morris

This study investigates the role of Atg16l1 in skin homeostasis using LAP-deficient mice, finding no significant cutaneous phenotype despite histological differences.

DOI 10.1016/j.xjidi.2024.100283

mouseexperimental assay

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Systems BiologyDisease Models & MechanismsPeer-reviewedJan 1, 2019

Integrative analysis of Paneth cell proteomic and transcriptomic data from intestinal organoids reveals functional processes dependent on autophagy

Emily J. Jones, Zoe J. Matthews, Lejla Gul…·Tamas Douglas Korcsmaros

The paper integrates proteomic and transcriptomic data from intestinal organoids to identify autophagy-dependent processes in Paneth cells, showing that autophagy impairment affects protein abundance and key cellular functions.

25 citations

mouseproteomics

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