Reinat Nevo

The paper investigates how extrachromosomal DNA (ecDNA) inheritance mechanisms influence cancer evolution through mitotic segregation and micronuclei formation.

This paper shows that STAT5A deficiency disrupts actin networks, leading to mitochondrial dysfunction and IFN-beta production, which can be reversed by restoring ACTN1.

The paper shows cancer-associated fibroblasts suppress NK cell cytotoxicity by acting as decoys, leading to poor disease outcomes in breast cancer.

The paper shows that C-terminal tails of membrane proteins influence post-translational insertion of transmembrane helices, with sequence changes causing functional defects and disease.

The paper examines how stress affects gene expression variability in yeast populations and identifies two distinct modes of proteomic adaptation with different fitness outcomes.

This study shows PTBP1 is expressed in adult sensory and motor neurons, with increased axonal levels after injury, affecting axon outgrowth and sensation.