Seil Jang

This study shows that RcSxph from American bullfrogs can counteract saxitoxin poisoning in mice by binding the toxin, validating its role as a toxin sponge.

This paper presents cryo-EM structures of human K2P13.1 (THIK-1) revealing a novel hydrophilic pore restriction and lipid cofactor site, with implications for modulator development.

This paper develops a chemogenetic method to irreversibly activate K2P channels, enabling studies of their function and potential therapeutic applications.