Author
Priya Pancholi
Memorial Sloan Kettering Cancer CenterORCID 0009-0000-9863-130XUnclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2022-2026 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 15 mutual co-author links4 papers
Recent·Most cited
- Cell BiologybioRxivPreprint
Diet induced insulin resistance is due to induction of PTEN expression
Radha Mukherjee, Priya Pancholi, Malvika Sharma…·Neal X. Rosen
The paper shows that diet-induced insulin resistance results from increased PTEN expression, which inhibits PI3K signaling, and that PTEN and mTORC1 inhibitors can reverse this effect.
2 citations - Cancer BiologyCancer ResearchPeer-reviewed
Tumorigenesis driven by the BRAF V600E oncoprotein requires secondary mutations that overcome its feedback inhibition of migration and invasion
Sunyana Gadal, Jacob A. Boyer, Simon F. Roy…·Neal X. Rosen
This study shows that BRAFV600E mutations inhibit cell migration and invasion through feedback inhibition of RAC1, requiring secondary mutations to overcome this block and enable tumorigenesis.
7 citations - Systems BiologybioRxivPreprint
Discovery of novel therapeutic targets in cancer using patient-specific gene regulatory networks.
Andre Neil Forbes, Duo Xu, Sandra M. Cohen…·Ekta Khurana
The paper identifies novel drug targets in cancer by constructing patient-specific gene regulatory networks using ATAC-seq and RNA-seq data.