Author

Keegan A. Christensen

University of IowaORCID 0009-0002-4460-444XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Agata GruszczyńskaiD· 1 shared Ashutosh KumariD· 1 shared Bryan G. AlleniD· 1 shared Claudia Robles-PlanellsiD· 1 shared Conner R. YorkiD· 1 shared David H. SpenceriD· 1 shared Dijie LiuiD· 1 shared Douglas R. SpitziD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperCancer Biology

Agata GruszczyńskaORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Cancer BiologyRadiation ResearchPeer-reviewedJul 3, 2025

Targeting CXCR4 with -Pentixather Significantly Increases Overall Survival in Small Cell Lung Cancer

Keegan A. Christensen, Melissa A. Fath, Jordan T. Ewald…·Douglas R. Spitz

This study shows that [212Pb/203Pb]-pentixather targeting CXCR4 improves survival in SCLC xenografts and causes temporary bone marrow cytopenias that resolve.

5 citations

mouseexperimental assay

𝕏 PostBluesky

Cancer BiologyClinical Cancer ResearchPeer-reviewedJun 7, 2024

Missense mutations in Myc Box I influence MYC cellular localization, mRNA partitioning and turnover to promote leukemogenesis

Nancy B.J. Arthur, Keegan A. Christensen, Kathleen Mannino…·Francesca Ferraro

This study shows that MBI MYC mutations alter MYC localization and disrupt mRNA subcellular distribution and turnover, promoting leukemogenesis.

6 citations

mousebulk RNA-seq

𝕏 PostBluesky