Author

Nancy B.J. Arthur

Washington University in St. LouisORCID 0000-0001-9065-657XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:metabolomics· 1

Frequent Co-Authors

Conner R. YorkiD· 2 shared Stephen Matthew SykesiD· 2 shared Aaron R. GoldmaniD· 1 shared Agata GruszczyńskaiD· 1 shared Ashutosh KumariD· 1 shared David H. SpenceriD· 1 shared Francesca FerraroiD· 1 shared Francesca FerraroiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCancer Biology

Conner R. YorkORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintMar 20, 2026

Targeting MTHFD2 disrupts mitochondrial redox homeostasis and restores venetoclax sensitivity in acute myeloid leukemia

Judith O. Sokei, Orsola di Martino, Mary Basse…·Stephen Matthew Sykes

This study identifies MTHFD2 as a critical mitochondrial enzyme in AML that supports redox homeostasis and therapeutic resistance, showing that its inhibition restores venetoclax sensitivity.

DOI 10.64898/2026.03.18.712743

mousehuman

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Cancer BiologyClinical Cancer ResearchPeer-reviewedJun 7, 2024

Missense mutations in Myc Box I influence MYC cellular localization, mRNA partitioning and turnover to promote leukemogenesis

Nancy B.J. Arthur, Keegan A. Christensen, Kathleen Mannino…·Francesca Ferraro

This study shows that MBI MYC mutations alter MYC localization and disrupt mRNA subcellular distribution and turnover, promoting leukemogenesis.

6 citations

mousebulk RNA-seq

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