BiophysicsNature CommunicationsPeer-reviewed
Structure and function of the SIT1 proline transporter in complex with the COVID-19 receptor ACE2
Huanyu Z. Li, Ashley C. W. Pike, Irina Lotsaris…·David Bryant Sauer
The paper determines the structure of the SIT1 proline transporter complexed with ACE2 using cryo-EM, revealing substrate specificity and structural changes related to transport and a disease-causing mutation.
19 citations