Author
Walter and Eliza Hall Institute of Medical ResearchORCID 0009-0005-1004-9435Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Shene Chiou, Christopher R. Horne, Komal M. Patel…·James M. Murphy
This study compares three RIPK3 kinase-dead variants to show that their scaffolding functions differ based on kinase domain conformation, not just kinase activity, and highlights implications for inhibitor development.
Shene Chiou, Aysha Al‐Ani, Yi Pan…·André L. Samson
The paper develops automated immunohistochemistry protocols to detect necroptotic pathway proteins in mouse and human tissues, revealing heterogeneity and disease-related changes in expression.
Hui San Chin, Mark F. van Delft, Robert L. Ninnis…·Grant Dewson
This study identifies VDAC2 as essential for BAX-mediated apoptosis and tumor suppression, showing BAX and BAK are differentially regulated.